Alectinib (Alecnib) is a medication used in the treatment of non-small cell lung cancer (NSCLC), specifically targeting tumors that are positive for a genetic mutation known as ALK (anaplastic lymphoma kinase) and, in some cases, ROS1 rearrangements. It belongs to a class of drugs called ALK inhibitors. Alectinib works by blocking the activity of the ALK protein, which is involved in the growth and spread of cancer cells. Alectinib is often prescribed for patients who haven't responded to other treatments like Crizotinib.

It's often prescribed for patients who have either not responded to or have experienced progression while on crizotinib, another ALK inhibitor. Alectinib has demonstrated efficacy in controlling the growth of tumors in such patients, and it has shown promising results in clinical trials, including improved progression-free survival compared to standard chemotherapy.

As with any medication, alectinib can cause side effects, including fatigue, constipation, muscle weakness, swelling, and abnormal liver function tests. It's typically taken orally, and the dosage can vary depending on individual patient factors and the specific cancer being treated.

It's essential for patients to discuss potential side effects and any concerns with their healthcare provider before starting alectinib treatment. Additionally, regular monitoring and follow-up appointments are typically recommended to assess the treatment's effectiveness and manage any side effects that may arise.

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