Tramadol, a potent painkiller, is used to relieve moderate to severe pain that cannot be managed by other medications. Tramadol, a synthetic opioid, works on the spine and brain to reduce pain perception.
In order to control pain continuously, tramadol is also available in an extended-release version. The as-needed treatment of pain with tramadol in this form is not recommended.
In addition to acting at the opioid pain receptor, tramadol decreases the absorption of two neurotransmitters, norepinephrine and serotonin, which may improve its pain-relieving effects, though the specific mechanism is unknown.
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